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It is used medically to treat liver damage from conditions like fatty liver disease, alcohol abuse, and drug overdoses (e.g., acetaminophen)

GMX1777 is a cyanoguanidine compound that is rapidly converted into the active form GMX1778, a competitive inhibitor of NAMPT

Given its origin in gastric juice, BPC-157 has been studied for protecting and healing the gut lining, including in models of inflammatory bowel conditions and NSAID-induced damage

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Below, we examine key mechanisms underlying neuronal degeneration, highlighting how they drive cellular damage (Figure 1)